Barbiturates are central nervous system depressants. They are used therapeutically as sedatives,
hypnotics, and anticonvulsants. Barbiturates are almost always taken orally as capsules or tablets. The
effects resemble those of intoxication with alcohol. Chronic use of barbiturates leads to tolerance and
physical dependence.
Short acting Barbiturates taken at 400 mg/day for 2-3 months produces a clinically significant degree of
physical dependence. Withdrawal symptoms experienced during periods of drug abstinence can be
severe enough to cause death.
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